{"id":1529,"date":"2022-06-10T14:55:52","date_gmt":"2022-06-10T17:55:52","guid":{"rendered":"https:\/\/new-website.wecann.academy\/2022\/06\/10\/medical-cannabis-and-chronic-pain-the-use-of-the-plant-to-reduce-symptoms\/"},"modified":"2025-10-19T23:31:07","modified_gmt":"2025-10-20T02:31:07","slug":"medical-cannabis-and-chronic-pain-the-use-of-the-plant-to-reduce-symptoms","status":"publish","type":"post","link":"https:\/\/wecann.academy\/en\/medical-cannabis-and-chronic-pain-the-use-of-the-plant-to-reduce-symptoms\/","title":{"rendered":"Medical cannabis and chronic pain: the use of the plant to reduce symptoms"},"content":{"rendered":"<p><span ><span><span style=\"color: #222222\">It is estimated that at least <\/span><\/span><a target=\"_blank\" href=\"https:\/\/agenciabrasil.ebc.com.br\/saude\/noticia\/2018-09\/dor-cronica-afeta-pelo-menos-37-dos-brasileiros\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>37% of the Brazilian population experience chronic pain<\/strong><\/span><\/span><\/a><span><span style=\"color: #222222\">according to the Brazilian Society for the Study of Pain (SBED). The classification takes into account pain that persists or recurs for more than three months and the causes are most often related to chronic diseases, such as osteodiscodegenerative diseases, neurological disorders and cancer. Treatment is usually carried out with drugs, physiotherapy and psychotherapy, but other adjuvants often need to be considered. The use of <strong>Medical Cannabis in the management of chronic pain<\/strong> has been widely studied and there are several benefits of cannabinoid derivatives for this condition.\u00a0<\/p>\n<h2><span style=\"color: #7a7a7a\"><span style=\"font-size: 32pt\"><span>What is the evidence for the use of Cannabis in chronic pain?\u00a0<\/h2>\n<p><span ><span><span style=\"color: #222222\">First of all, it is important to know more about the <\/span><\/span><a target=\"_blank\" href=\"https:\/\/wecann.academy\/en\/sistema-endocanabinoide\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>Endocannabinoid System<\/span><\/span><\/a><span><span style=\"color: #222222\">. SE is a <strong>vital regulatory system<\/strong>, present in humans and all vertebrate animals, which is involved in almost all of our physiological and pathological processes.\u00a0<\/p>\n<p><span ><span><span style=\"color: #222222\">The interaction of endocannabinoid receptors with their main ligands regulates and modulates stress, emotions, digestion, cardiovascular functions, the immune system, inflammatory processes and also pain.<\/p>\n<p><span ><span><span style=\"color: #222222\"><strong>This interaction can be stimulated by chemical compounds present in Cannabis<\/strong> \u2014 <\/span><\/span><a target=\"_blank\" href=\"https:\/\/wecann.academy\/en\/fitocanabinoide\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>the plant&#8217;s phytocannabinoids <\/span><\/span><\/a><span><span style=\"color: #222222\">and terpenes can help balance the functional tone of this system. Therefore, medicinal cannabis can be an important ally in the management of chronic pain.\u00a0<\/p>\n<p><span ><span><span style=\"color: #222222\">A review published in<\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33729211\/\" rel=\"noopener\"><span><u> <\/u><span style=\"color: #2ecc71\">July 2021<\/span><\/span><\/a><span><span style=\"color: #222222\"> concludes that there is substantial evidence from preclinical studies that<strong> cannabinoids hold great promise for the development of analgesic drugs<\/strong>. The authors also point out that further studies are needed to better understand the pharmacology and therapeutic potential of other phytocannabinoids, in addition to the main THC and CBD \u2014 and how other plant chemical elements interact with both in analgesia.\u00a0<\/p>\n<p><span ><span><span style=\"color: #222222\"><strong> Check at <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33729211\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies.<\/strong><\/span><\/span><\/a><\/span><\/p>\n<p><span ><span><span style=\"color: #222222\">This <\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33409086\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>study<\/span><\/span><\/a><span><span style=\"color: #222222\"> from 2020, properly depicts such potential. The authors evaluated the use of medicinal cannabis in patients with chronic pain who <\/span><\/span><a target=\"_blank\" href=\"https:\/\/wecann.academy\/en\/reducao-no-uso-de-opioides\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>regularly take opioids<\/span><\/span><\/a><span><span style=\"color: #222222\">. For at least 3 months, more than 500 patients have used cannabis in combination with previously prescribed opioid drugs to treat chronic pain. In relation to opioids:\u00a0<\/p>\n<ul>\n<li style=\"list-style-type: disc\"><span ><span><span style=\"color: #222222\">40.4% of respondents interrupted use;<\/li>\n<li style=\"list-style-type: disc\"><span ><span><span style=\"color: #222222\">45.2% reported some decrease to the use;<\/li>\n<li style=\"list-style-type: disc\"><span ><span><span style=\"color: #222222\">3.3% did not manage any changes to the substance use;<\/li>\n<li style=\"list-style-type: disc\"><span ><span><span style=\"color: #222222\">1.1% increased ingestion.\u00a0<\/li>\n<\/ul>\n<p><span ><span><span style=\"color: #222222\"><strong>Most reported improvement in functional capacity (80%) and quality of life (87%). <\/strong>Nearly half (48.2%) described a 40 to 100% reduction in pain.<\/p>\n<p><span ><span><span style=\"color: #222222\"><strong> Read more in: <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33409086\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>A Survey on the Effect That Medical Cannabis Has on Prescription Opioid Medication Usage for the Treatment of Chronic Pain at Three Medical Cannabis Practice Sites<\/strong><\/span><\/span><\/a><\/span><\/p>\n<p class=\" translation-block\"><span ><span><span style=\"color: #222222\">Results from an observational and longitudinal <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33764103\/\" target=\"_self\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>study<\/span><\/span><\/a><span><span style=\"color: #222222\"> , also from 2021, point out <b>that exposure to THC is related to pain improvement<\/b>, while CBD is associated with an improvement in mood \u2014 consequently, decreasing unpleasant sensations associated with pain. Aspects such as pain, clinical status, sleep pattern, quality of life and use of conventional drugs in patients with chronic pain who also used medicinal cannabis in their treatment were evaluated.<\/span><\/span><\/p>\n<p><span ><span><span style=\"color: #222222\"><strong> See <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33764103\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>No pain, all gain? Interim analyses from a longitudinal, observational study examining the impact of medical cannabis treatment on chronic pain and related symptoms<\/strong><\/span><\/span><\/a><\/span><\/p>\n<h3><span style=\"color: #7a7a7a\"><span style=\"font-size: 16pt\"><span>Cannabis and migraine<\/h3>\n<p><span ><span><span style=\"color: #222222\"><strong>Nine out of 10 migraine patients can get pain relief by inhaling cannabis. <\/strong>The finding is from a <\/span><\/span><a target=\"_blank\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S2095496420300741\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>study<\/span><\/span><\/a><span><span style=\"color: #222222\"> in which researchers followed the effects of the inhaled plant in 699 people with migraine, for 32 months. 94% of patients reported symptom relief within two hours after inhalation. Cannabis varieties with THC content equal to or greater than 10% were found to be more effective in pain relief.\u00a0<\/p>\n<p><span ><span><span style=\"color: #222222\"><strong> Learn more: <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S2095496420300741\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>Alleviative effects of Cannabis flower on migraine and headache<\/strong><\/span><\/span><\/a><\/span><\/p>\n<p><span ><span><span style=\"color: #222222\"><strong>Other studies also demonstrate the promising potential of using cannabinoid derivatives in migraine patients. <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/www.forbes.com\/sites\/ajherrington\/2021\/02\/17\/study-finds-cbd-is-an-effective-treatment-for-migraine\/?sh=af081d57ddc0\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>Preliminary results<\/span><\/span><\/a><span><span style=\"color: #222222\"> from a study carried out in 2020 indicate that 86% of patients who suffered from headaches reported improvement in their symptoms after using CBD oil in a 30-day treatment.<\/p>\n<p><span ><span><span style=\"color: #222222\">Using data from a medical cannabis application used by patients to track symptoms before and after using the plant, <\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31715263\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>researchers<\/span><\/span><\/a><span><span style=\"color: #222222\"> reported that there are significant reductions in signs of migraine and headaches after using the plant.<strong> Inhaled cannabis decreased pain intensity associated with migraine by approximately 50%.<\/strong><\/p>\n<p><span ><span><span style=\"color: #222222\"><strong> Read in: <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31715263\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>Short- and Long-Term Effects of Cannabis on Headache and Migraine<\/strong><\/span><\/span><\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><span style=\"color: #7a7a7a\"><span style=\"font-size: 16pt\"><span>Cannabis and fibromyalgia\u00a0<\/h3>\n<p><span ><span><span style=\"color: #222222\">Israeli researchers studied the association between cannabis and chronic pain in patients at two medical centers specializing in the treatment of <\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29461346\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>fibromyalgia<\/span><\/span><\/a><span><span style=\"color: #222222\">. After 10 to 11 months of treatment with cannabis, <strong>100% dos respondentes tiveram melhora nos sintomas da doen\u00e7a em todos os quesitos do question\u00e1rio<\/strong>, with better results in those related to pain. At least 50% of them reported having stopped using other drugs after starting medical cannabis. Adverse effects were reported by 30% of patients, but all were considered mild\u2014headaches, nausea, excessive hunger, dry mouth, and drowsiness.<\/p>\n<p><span ><span><span style=\"color: #222222\"><strong> Refer to the study: <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29461346\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>Medical Cannabis for the Treatment of Fibromyalgia<\/strong><\/span><\/span><\/a><\/span><\/p>\n<p><span ><span><span style=\"color: #000000\">Cannabis extracts with a higher concentration of THC <strong>can reduce pain<\/strong> and <strong>considerably improve the quality of life <\/strong>of people with <\/span><\/span><a target=\"_blank\" href=\"https:\/\/wecann.academy\/en\/cannabis-e-fibromialgia\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>fibromyalgia<\/span><\/span><\/a><span><span style=\"color: #000000\">. This is what a <\/span><\/span><a target=\"_blank\" href=\"https:\/\/academic.oup.com\/painmedicine\/article\/21\/10\/2212\/5942556\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>controlled, randomized, double-blind clinical study<\/span><\/span><\/a><span><span style=\"color: #000000\"> from October 2020 proves. The research was conducted by physicians from the Federal University of Santa Catarina (UFSC). Within 8 weeks of treatment, the<strong> group using medical cannabis had a decrease in fibromyalgia severity from 75 to 30<\/strong>while patients receiving placebo recorded a decrease from 70 to 61\u2014a scale of 0 to 100 on the <\/span><span style=\"color: #00796b\">and<\/span><span style=\"color: #000000\">score <\/span><\/span><a target=\"_blank\" href=\"https:\/\/www.scielo.br\/j\/rbr\/a\/VbJNBxFTfpn6PTTMwhpDBpB\/?lang=pt\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><em>Fibromyalgia Impact Questionnaire (FIQ)<\/em> (FIQ)<\/span><\/span><\/a><span><span style=\"color: #000000\">.\u00a0<\/p>\n<p><span ><span><span style=\"color: #000000\">An interesting point of the study is that it used a \u201chandmade preparation\u201d. Thus, the authors also conclude that phytocannabinoids, in addition to being efficient, <strong>can be a low-cost therapy<\/strong>.<\/p>\n<p><span ><span><span style=\"color: #000000\"><strong> Refer to the study <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/academic.oup.com\/painmedicine\/article\/21\/10\/2212\/5942556\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>Ingestion of a THC-Rich Cannabis Oil in People with Fibromyalgia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.<\/strong><\/span><\/span><\/a><\/span><\/p>\n<h2><span style=\"color: #7a7a7a\"><span style=\"font-size: 32pt\"><span>Cannabis and neuropathic pain\u00a0<\/h2>\n<p><span ><a target=\"_blank\" href=\"https:\/\/www.scielo.br\/j\/rdor\/a\/wzqPzvnbYFDD5DThvFXbwBC\/?lang=pt&#038;format=pdf\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>Researchers estimate<\/span><\/span><\/a><span><span style=\"color: #000000\"> that the neuropathic component may be present in about 35% of all pain syndromes. The patient has a tingling, burning sensation or hypersensitivity to touch or cold.<\/p>\n<p><span ><span><span style=\"color: #000000\">In <\/span><\/span><a target=\"_blank\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7027889\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>pre-clinical studies<\/span><\/span><\/a><span><span style=\"color: #000000\"> with rodents, it was observed that <strong>activation of endocannabinoid receptors was able to reduce chronic neuropathic inflammatory pain.<\/strong> Other research in animal models showed that, after treatment with CBD for 7 days, there was normalization of serotonergic neurotransmission (5-HT), reduction of mechanical allodynia and reduction of anxiety behavior.<\/p>\n<p><span ><span><span style=\"color: #000000\"><strong> Learn more at <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7027889\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>A Review of Scientific Evidence for THC:CBD Oromucosal Spray (Nabiximols) in the Management of Chronic Pain<\/strong><\/span><\/span><\/a><\/span><\/p>\n<p class=\" translation-block\"><span ><span style=\"font-family: Arial\"><span style=\"color: #000000\">In this randomized, double-blind clinical trial, when administering treatment with THC and CBD for 4 weeks in 125 patients with neuropathic pain of peripheral origin, researchers noticed a <b>significant reduction in the pain score<\/b>. They also observed significant improvements in other parameters, such as neuropathic pain scores (Neuropathic Pain Score), Pain Disability Index and patient&#8217;s global impression of change (Patient&#8217;s Global Impression of Change). Adverse effects reported were mainly sedative or gastrointestinal. <\/p>\n<p><span ><span><span style=\"color: #000000\"><strong> See: <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17997224\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>Sativex successfully treats neuropathic pain characterised by allodynia: a randomised, double-blind, placebo-controlled clinical trial<\/strong><\/span><\/span><\/a><\/span><\/p>\n<p><span ><span><span style=\"color: #000000\">A group consisting of pain specialists, psychiatrists, scientists and patients came together to assess the <strong>relationship between the benefit and safety of 12 pharmacological treatments for the management of chronic neuropathic pain<\/strong>, including cannabis-based medications. The <\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33998895\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>result<\/span><\/span><\/a><span><span style=\"color: #000000\">, published in 2021, indicates that <strong>cannabis-based medications achieved the highest score, ahead of <\/strong>medications often prescribed to these patients such as duloxetine, gabapentinoids, amitriptyline, tramadol, ibuprofen, among others.\u00a0<\/p>\n<p><span ><span><span style=\"color: #000000\"><strong> Read the whole study: <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33998895\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>A Multicriteria Decision Analysis Comparing Pharmacotherapy for Chronic Neuropathic Pain, Including Cannabinoids and Cannabis-Based Medical Products<\/strong><\/span><\/span><\/a><\/span><\/p>\n<h3><span style=\"color: #7a7a7a\"><span style=\"font-size: 16pt\"><span>Cancer Pain and Cannabis<\/h3>\n<p><span ><span><span style=\"color: #222222\">In the analysis <\/span><\/span><a target=\"_blank\" href=\"https:\/\/wecann.academy\/en\/cannabis-e-oncologia-pediatrica\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>\u201cShould oncologists recommend cannabis?\u201d<\/span><\/span><\/a><span><span style=\"color: #222222\">the author highlights the recommendation to prescribe a drug based on cannabis in the refractoriness of the use of other drugs for<strong>patients who developed peripheral neuropathy induced by chemotherapy.\u00a0<\/strong><\/p>\n<p><span ><span><span style=\"color: #222222\">It is noteworthy that <strong>medicinal cannabis has a <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/wecann.academy\/en\/reducao-no-uso-de-opioides\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>synergy of action with opioids<\/strong><\/span><\/span><\/a><span><span style=\"color: #222222\"><strong>, normally prescribed to control pain associated with cancer.<\/strong> Most patients with chronic pain, who regularly use opioids and start treatment with plant derivatives, manage to prevent the development of tolerance to opioids, avoiding the progressive increase in the dosage of these drugs.<\/p>\n<p><span ><span><span style=\"color: #222222\"><strong> Read more: <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31161270\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>Should Oncologists Recommend Cannabis?<\/strong><\/span><\/span><\/a><\/span><\/p>\n<p><span ><span><span style=\"color: #222222\">Al\u00e9m da <\/span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\">dor cr\u00f4nica, outros sintomas s\u00e3o relatados com frequ\u00eancia pelos pacientes de diversos tipos de c\u00e2ncer. S\u00e3o eles a <strong>fatigue<\/strong>to <strong>ins\u00f4nia <\/strong>and the <strong>inapet\u00eancia<\/strong>. Tamb\u00e9m n\u00e3o s\u00e3o raros os quadros de <a target=\"_blank\" href=\"https:\/\/wecann.academy\/en\/conceitos-prescritivos-e-ansiedade\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><span style=\"background-color: #ffffff\"><strong>anxiety<\/strong><\/a><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\">, <strong>depression<\/strong>, <strong>n\u00e1useas <\/strong>and <strong>v\u00f4mitos<\/strong>, consequ\u00eancias naturais dos protocolos de radio e quimioterapia.\u00a0<\/span><\/p>\n<p class=\" translation-block\"><span ><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\">All these symptoms associated with cancer and the side effects resulting from its treatment can be improved with the use of medicinal cannabis as a therapeutic adjuvant in the oncological context. This is demonstrated by the promising <a target=\"_self\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31413731\/\" rel=\"noopener\"><span><span style=\"color: #2ecc71\"><span style=\"background-color: #ffffff\">results<\/a><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\"> of research that reinforce the plant&#8217;s potential in this context.<\/span><\/p>\n<p><span ><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\"><strong> See <\/strong><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31413731\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><span style=\"background-color: #ffffff\"><strong>Opportunities for cannabis in supportive care in cancer<\/strong><\/a><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\"><strong>, published in 2019.<\/strong><\/span><\/p>\n<p><span ><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\">Want more data? How about the results of this study <a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29482741\/\" rel=\"noopener\"><span><span style=\"color: #2ecc71\"><span style=\"background-color: #ffffff\">published in 2018<\/a><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\">, which evaluated a group of <strong>2,970 cancer patients<\/strong> treated with medical cannabis between 2015 and 2017? After six months of follow-up with cannabis therapy, patients responded as follows:<\/span><\/p>\n<ul>\n<li style=\"list-style-type: disc\"><span ><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\"><strong>95.9% of them reported an overall improvement in their condition<\/strong>,\u00a0<\/span><\/li>\n<li style=\"list-style-type: disc\"><span ><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\">3.7% did not report any changes and\u00a0<\/span><\/li>\n<li style=\"list-style-type: disc\"><span ><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\">0.3% reported worsening of their medical condition.<\/span><\/li>\n<\/ul>\n<p><span ><span><span style=\"color: #000000\"><span style=\"background-color: #ffffff\">To get deeper into the potential of cannabinoid derivatives in the cancer context, read our article on <a target=\"_blank\" href=\"https:\/\/wecann.academy\/en\/cannabis-e-cancer\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><span style=\"background-color: #ffffff\">Cannabis as adjuvant therapy in cancer patients<\/a><\/span><\/p>\n<h3><span style=\"color: #7a7a7a\"><span style=\"font-size: 16pt\"><span>Pelvic Pain and Cannabis<\/h3>\n<p><span ><span style=\"font-family: Arial\"><span style=\"color: #222222\"><span style=\"background-color: #ffffff\">The analgesic and anti-inflammatory properties of phytocannabinoids also appear as a safe and effective alternative for relieving frequent and intense pain, prevalent in the pelvic region.<span><span style=\"color: #222222\"> Cannabis-based medications may be beneficial in the treatment of<strong> chronic pelvic pain, especially when associated with endometriosis. To read more about this topic, check out our post on <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/wecann.academy\/en\/cannabis-medicinal-para-mulheres\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>Medical Cannabis for Women.<\/strong><\/span><\/span><\/a><span><span style=\"color: #222222\"><strong>\u00a0<\/strong><\/p>\n<p><span ><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33252316\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>A study from 2020<\/span><\/span><\/a><span><span style=\"color: #222222\"> showed that <strong>20% of patients who participated in the survey reported using the plant to alleviate chronic pelvic pain,<\/strong> especially symptoms of pain, muscle spasms, irritability, anxiety and depression symptoms, sleep disorder and reduced libido.<\/p>\n<p><span ><span><span style=\"color: #222222\"><strong> See <\/strong><\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33252316\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span><strong>Use of Cannabis for Self-Management of Chronic Pelvic Pain<\/strong><\/span><\/span><\/a><\/span><\/p>\n<p class=\" translation-block\"><span ><span><span style=\"color: #222222\"> are just some of the existing evidence regarding the therapeutic potential of cannabis in the management of chronic pain. In 2017, The Health Effects of Cannabis and Cannabinoids by the US National Academy of Sciences, Engineering and Medicine concluded that there is substantial conclusive scientific evidence for the use of cannabinoids in chronic pain.<\/p>\n<p><span ><span><span style=\"color: #222222\">If you want to learn more about the subject and incorporate this valuable therapeutic tool into your practice, check out the WeCann Academy&#8217;s <\/span><span style=\"color: #2ecc71\">C<\/span><\/span><a target=\"_blank\" href=\"https:\/\/wecann.academy\/en\/cursos\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>International Certification<\/span><\/span><\/a><span><span style=\"color: #222222\"> in Endocannabinoid Medicine.\u00a0<\/p>\n<p><span ><span><span style=\"color: #000000\"><strong>References<\/strong><\/p>\n<p><span style=\"font-size: 12px\"><span style=\"color: #7a7a7a\"><span>Abrams DI. <\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31161270\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>Should Oncologists Recommend Cannabis?.<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span> Curr Treat Options Oncol. 2019;20(7):59. Published 2019 Jun 3. doi:10.1007\/s11864-019-0659-9<\/p>\n<p><span style=\"font-size: 12px\"><span style=\"color: #7a7a7a\"><span>ALBUQUERQUE, Fl\u00e1via. <\/span><\/span><a target=\"_blank\" href=\"https:\/\/agenciabrasil.ebc.com.br\/saude\/noticia\/2018-09\/dor-cronica-afeta-pelo-menos-37-dos-brasileiros\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>Dor cr\u00f4nica afeta pelo menos 37% dos brasileiros.<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span> Ag\u00eancia Brasil, 2018. Dispon\u00edvel em: <<\/span><\/span><a target=\"_blank\" href=\"https:\/\/agenciabrasil.ebc.com.br\/saude\/noticia\/2018-09\/dor-cronica-afeta-pelo-menos-37-dos-brasileiros\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>https:\/\/agenciabrasil.ebc.com.br\/saude\/noticia\/2018-09\/dor-cronica-afeta-pelo-menos-37-dos-brasileiros<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span>>. Acesso em: 26 de julho de 2021.<\/p>\n<p><span style=\"font-size: 12px\"><span style=\"color: #7a7a7a\"><span>Carolina Chaves, MD, Paulo Cesar T Bittencourt, MD, MSc, Andreia Pelegrini, PhD, <\/span><\/span><a target=\"_blank\" href=\"https:\/\/academic.oup.com\/painmedicine\/article\/21\/10\/2212\/5942556\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>Ingestion of a THC-Rich Cannabis Oil in People with Fibromyalgia: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span>, Pain Medicine, Volume 21, Issue 10, October 2020, Pages 2212\u20132218, <\/span><\/span><a target=\"_blank\" href=\"https:\/\/doi.org\/10.1093\/pm\/pnaa303\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>https:\/\/doi.org\/10.1093\/pm\/pnaa303<\/span><\/span><\/a><\/span><\/p>\n<p><span style=\"font-size: 12px\"><span style=\"color: #7a7a7a\"><span>Cuttler C, Spradlin A, Cleveland MJ, Craft RM. <\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31715263\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>Short- and Long-Term Effects of Cannabis on Headache and Migraine<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span>. J Pain. 2020;21(5-6):722-730. doi:10.1016\/j.jpain.2019.11.001<\/p>\n<p><span style=\"font-size: 12px\"><span style=\"color: #7a7a7a\"><span>Finn DP, Haroutounian S, Hohmann AG, Krane E, Soliman N, Rice ASC. <\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33729211\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>Cannabinoids, the endocannabinoid system, and pain: a review of preclinical studies.<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span> Pain. 2021;162(Suppl 1):S5-S25. doi:10.1097\/j.pain.0000000000002268<\/p>\n<p><span style=\"font-size: 12px\"><span style=\"color: #7a7a7a\"><span>Gruber SA, Smith RT, Dahlgren MK, Lambros AM, Sagar KA.<\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33764103\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span> No pain, all gain? Interim analyses from a longitudinal, observational study examining the impact of medical cannabis treatment on chronic pain and related symptoms.<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span> Exp Clin Psychopharmacol. 2021;29(2):147-156. doi:10.1037\/pha0000435<\/p>\n<p><span style=\"font-size: 12px\"><span style=\"color: #7a7a7a\"><span>Habib G, Artul S. <\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29461346\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>Medical Cannabis for the Treatment of Fibromyalgia<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span>. J Clin Rheumatol. 2018;24(5):255-258. doi:10.1097\/RHU.0000000000000702<\/p>\n<p><span style=\"font-size: 12px\"><span style=\"color: #7a7a7a\"><span>HERRINGTON, A.J. Study Finds CBD Is An Effective Treatment For Migraine. Forbes, 2021. Dispon\u00edvel em: <<\/span><\/span><a target=\"_blank\" href=\"https:\/\/www.forbes.com\/sites\/ajherrington\/2021\/02\/17\/study-finds-cbd-is-an-effective-treatment-for-migraine\/?sh=af081d57ddc0\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>https:\/\/www.forbes.com\/sites\/ajherrington\/2021\/02\/17\/study-finds-cbd-is-an-effective-treatment-for-migraine\/?sh=af081d57ddc0<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span>>. Acesso em: 11 de agosto de 2021.<\/p>\n<p><span style=\"font-size: 12px\"><span style=\"color: #7a7a7a\"><span>Sarah S. Stith, Jegason P. Diviant, Franco Brockelman, Keenan Keeling, Branden Hall, Storri Lucern, Jacob M. Vigil,<\/span><\/span><a target=\"_blank\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S2095496420300741\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span> Alleviative effects of Cannabis flower on migraine and headache<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span>,\u00a0Journal of Integrative Medicine, Volume 18, Issue 5, 2020, Pages 416-424, ISSN 2095-4964,\u00a0https:\/\/doi.org\/10.1016\/j.joim.2020.07.004.<\/p>\n<p><span style=\"font-size: 12px\"><span style=\"color: #7a7a7a\"><span>Takakuwa KM, Sulak D. <\/span><\/span><a target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33409086\/\" rel=\"noopener\"><span style=\"color: #2ecc71\"><span>A Survey on the Effect That Medical Cannabis Has on Prescription Opioid Medication Usage for the Treatment of Chronic Pain at Three Medical Cannabis Practice Sites. Cureus.<\/span><\/span><\/a><span style=\"color: #7a7a7a\"><span> 2020;12(12):e11848. Published 2020 Dec 2. doi:10.7759\/cureus.11848<\/p>\n","protected":false},"excerpt":{"rendered":"<p>It is estimated that at least 37% of the Brazilian population experience chronic painaccording to the Brazilian Society for the Study of Pain (SBED). The classification takes into account pain that persists or recurs for more than three months and the causes are most often related to chronic diseases, such as osteodiscodegenerative diseases, neurological disorders [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1393,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1529","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sem-categoria"],"acf":[],"_links":{"self":[{"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/posts\/1529","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/comments?post=1529"}],"version-history":[{"count":4,"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/posts\/1529\/revisions"}],"predecessor-version":[{"id":3539,"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/posts\/1529\/revisions\/3539"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/media\/1393"}],"wp:attachment":[{"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/media?parent=1529"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/categories?post=1529"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wecann.academy\/en\/wp-json\/wp\/v2\/tags?post=1529"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}