In the review <\/span><\/span>Medical marijuana in pediatric oncology: A review<\/em><\/strong><\/span><\/span><\/a>\u00a0<\/span>of the evidence and implications for practice,<\/em><\/strong><\/span><\/span><\/a>the authors highlight the potential for medicinal cannabis in caring for children with cancer. Check them out are.\u00a0<\/p>\n \u00a0<\/p>\n The article <\/span><\/span>Should Oncologists Recommend Cannabis?<\/em><\/span><\/span><\/a> tamb\u00e9m traz um compilado de estudos que refor\u00e7am o potencial da Cannabis medicinal no tratamento adjuvante ao c\u00e2ncer, explorando os seguintes t\u00f3picos:<\/p>\n > Learn more at <\/strong><\/span><\/span>Should Oncologists Recommend Cannabis?<\/strong><\/span><\/span><\/a><\/span><\/p>\n Below, we detail some of these effects, referencing articles mentioned above and also other published works.\u00a0<\/p>\n \u00a0<\/p>\n In the United States, two randomized, double-blind trials, including pediatric cancer patients, demonstrated that delta-9-THC is a superior antiemetic to placebo.<\/strong>A third study even shows that THC has more benefits than prochlorperazine.<\/strong>.\u00a0<\/p>\n Read at:\u00a0<\/strong><\/p>\n > <\/strong><\/span><\/span>Delta-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate;<\/strong><\/span><\/span><\/a>;<\/strong><\/p>\n > <\/strong><\/span><\/span>Antiemetic effect of delta-9-tetrahydrocannabinol in patients receiving cancer chemotherapy.<\/strong><\/span><\/span><\/a>;<\/strong><\/p>\n > <\/strong><\/span><\/span>Antiemetics in patients<\/strong><\/span><\/span><\/a> receiving chemotherapy for cancer: a randomized comparison of<\/strong><\/span><\/span><\/a> delta-9-tetrahydrocannabinol and prochlorperazine<\/strong><\/span><\/span><\/a>.\u00a0<\/strong><\/p>\n \u00a0<\/p>\n Some cancers can cause you to lose appetite even in early stages. In advanced cases, this symptom ends up affecting 80% to 90% of patients. Weight loss in cancer is considered serious<\/strong>because it is also associated with loss of muscle mass and functional status.\u00a0<\/p>\n There are studies showing that <\/span><\/span>Medical Cannabis<\/span><\/span><\/a> and <\/span><\/span>its derivatives<\/span><\/span><\/a> have the potential to stimulate appetite in adults with HIV\/AIDS. <\/span>R<\/span><\/span>esearches<\/span><\/span><\/a>s<\/span> comparing dronabinol (a synthetic version of THC) to placebo also suggests that the cannabinoid derivative is more effective in fighting anorexia in patients with cancer.\u00a0<\/p>\n Check out the studies:\u00a0<\/strong><\/p>\n > <\/strong><\/span><\/span>Dronabinol and marijuana in HIV+ marijuana smokers: acute effects on caloric intake and mood<\/strong><\/span><\/span><\/a><\/span><\/p>\n > <\/strong><\/span><\/span>Dronabinol as a treatment for anorexia associated with weight loss in patients with AIDS<\/strong><\/span><\/span><\/a><\/span><\/p>\n > <\/strong><\/span><\/span>Delta-9-tetrahydrocannabinol may palliate altered chemosensory perception in cancer patients: results of a randomized, double-blind, placebo-controlled pilot trial<\/strong><\/span><\/span><\/a><\/span><\/p>\n \u00a0<\/p>\n A report from the National Academies of Sciences, Engineering and <\/em>Medicine (NASEM), <\/em>which represents a national collective scientific academy for the United States, supports the finding that adults with chronic pain treated with cannabinoid derivatives are more likely to have their pain symptoms reduced.<\/strong>.\u00a0<\/p>\n > Read at <\/strong><\/span><\/span>The health effects of cannabis and cannabinoids: the current state of evidence and recommendations for research.<\/strong><\/span><\/span><\/a>.<\/strong><\/p>\n Generally, <\/span><\/span>it is recommended<\/span><\/span><\/a> that when treating patients who have developed chemotherapy-induced peripheral neuropathy,<\/strong> a Cannabis-based drug is prescribed in refractory situations to the use of other drugs.\u00a0\u00a0<\/p>\n Another very important point is that <\/span><\/span>medicinal Cannabis shows synergy of action with opioids<\/strong><\/span><\/span><\/a>, often prescribed to control cancer pain. Most patients with chronic pain, who regularly make use of opioids and start treatment with medicinal cannabis, manage to prevent the development of tolerance to opioids and, consequently, avoid the need for increased dosage.<\/span><\/p>\n \u00a0<\/p>\n The same NASEM report also highlights evidence that cannabinoids improve sleep pattern <\/strong>of individuals with sleep disorders related to chronic pain, fibromyalgia, multiple sclerosis and obstructive sleep apnea syndrome.\u00a0<\/p>\n It is common for cancer patients to report difficulty sleeping. Studies show that people with pain-causing illnesses, including cancer pain and peripheral neuropathic pain, improved their sleep pattern when using THC- and CBD-based formulation (1:1).\u00a0<\/p>\n > Read at <\/strong><\/span><\/span>Cannabis, pain, and sleep: lessons from therapeutic clinical trials of Sativex, a cannabis-based medicine<\/strong><\/span><\/span><\/a><\/span><\/p>\n \u00a0<\/p>\n Seizures can be the first symptom of brain tumors in children and teenagers. <\/span><\/span>Clinical trials<\/span><\/span><\/a> have already proven that using CBD in the treatment of children with difficult-to-control seizure disorders is safe and effective.\u00a0<\/strong><\/p>\n > Learn more at <\/strong><\/span><\/span>Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome<\/strong><\/span><\/span><\/a>\u00a0<\/p>\n \u00a0<\/p>\n There is evidence that cannabinoid derivatives also have antineoplastic effects.<\/span><\/span> in vitro<\/em><\/span><\/span><\/a> and some <\/span><\/span>in vivo studies in vivo<\/em><\/span><\/span><\/a> have demonstrated antineoplastic potential in some of the most common malignant neoplasms in childhood and adolescence, such as lymphoma, leukemia, rhabdomyosarcoma, pheochromocytoma, glioblastoma, astrocytoma, neuroblastoma,<\/strong>, among others.\u00a0<\/p>\n Read at:\u00a0<\/strong><\/p>\n > Cannabinoids: potential anticancer agents<\/strong><\/span><\/span><\/a><\/span><\/p>\n > Anti-tumoral action of cannabinoids: involvement of sustained ceramide accumulation and extracellular signal-regulated kinase activation<\/strong><\/span><\/span><\/a><\/span><\/p>\n \u00a0<\/p>\n A <\/span><\/span>2021 study<\/strong><\/span><\/span><\/a> on the use of Cannabis in pediatric oncology provides data that may encourage other publications on this topic:\u00a0<\/p>\n Although there are still few studies with children and teenagers, clinical practice and research carried out with adults indicate that the use of Cannabis in children with cancer can bring several benefits to them.\u00a0<\/strong><\/p>\n The fact that medical Cannabis is already allowed in the treatment of children in most of the United States is further evidence that it is only a matter of time for us to have more documented therapeutic gains.\u00a0<\/p>\n \u00a0<\/p>\n If you’d like to stay up to date on medical Cannabis research, make sure that you’re following <\/span><\/span>our blog<\/span><\/span><\/a>And if you are interested in applying Endocannabinoid Medicine safely and effectively in your medical practice, subscribe to the <\/span><\/span>WeCann Academy\u2019s International Certificate in Endocannabinoid Medicine<\/span><\/span><\/a> We are a global community of studies in Endocannabinoid Medicine, which brings together specialists of national and international relevance joining scientific knowledge and practical experience in a highly qualified manner.<\/p>\n \u00a0<\/p>\nWhat are the possible benefits of cannabis in pediatric oncology?<\/h2>\n
\n
Antiemetic effect<\/strong><\/h3>\n
Appetite stimulant<\/strong><\/h3>\n
Adjuvant in chronic pain<\/strong><\/h3>\n
Adjuvant for insomnia and mood disorders<\/strong><\/h3>\n
Seizure Treatment\u00a0<\/strong><\/h3>\n
Antineoplastic potential<\/strong><\/h3>\n
<\/svg>” alt=”Cannabis como adjuvante terap\u00eautico no paciente com c\u00e2ncer” width=”901″ height=”181″ data-src=”https:\/\/wecann.academy\/wp-content\/uploads\/2021\/06\/CR04_CTAblog_Capa-1.png” \/><\/a><\/p>\n
\n
\n